SAFETY DATA SHEET. 1. Identification. Product identifier: DIMETHYLFORMAMIDE. Other means of identification. Product No.: , . View or download the N,N-Dimethylformamide MSDS (Material Safety Data Sheet) or SDS for from Merck. Print Date 05/08/ SECTION 1. PRODUCT AND COMPANY IDENTIFICATION. Product name.: N,N-Dimethylformamide. MSDS Number.

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Dimethylformamide – Wikipedia

DMF is a common solvent for chemical reactions. LD dimetgylformamide median dose. Encyclopedia of Reagents for Organic Synthesis. Also the spinning of polyurethane based elastomers is performed from DMF based solutions. In Trost, Barry M. DMF is also used as industrial paint stripper. DMF undergoes decarbonylation near its boiling point to give dimethylamine.

By using this site, you agree to the Terms of Use and Privacy Policy. Orders subjected to minimum order quantity. On a laboratory scale any thermal runaway is usually quickly noticed and brought under control with an ice bath and this remains a popular combination of reagents. Although currently impractical, DMF can be prepared from supercritical carbon dioxide using ruthenium -based catalysts.


HHHHH The acute LD50 oral, rats and mice is 2.

The pharmaceutical industry uses DMF as a reaction and crystallization solvent because of its exceptional solvency parameters. Distillation is therefore conducted under reduced pressure at lower temperatures.

In one of its main uses in organic synthesisDMF is a reagent in the Vilsmeier—Haack reactionwhich is used to formylate aromatic compounds. DMF is used in the production of acrylic fibers and plastics.

Retrieved 27 June This page was last edited on 12 Decemberat Substitution is permitted on the —NH 2 group. You may be trying to rimethylformamide this site from a secured browser on the server.


Annals of Internal Medicine. Views Read Edit View history. Retrieved from ” https: Dimethylformamide is odorless whereas technical grade or degraded dimethylfomramide often have a fishy smell due to impurity of dimethylamine.

As its name indicates, it is a derivative of formamidethe amide of formic acid. Product Description Dimethylformamide DMF is a clear, colorless, hygroscopic liquid with a slight amine odor.

Resources Active, excipient, and intermediate ingredients for pharmaceuticals Eastman ingredients for pharmaceuticals. This high solubility of inorganic substances also leads to the application of DMF in the production of high voltage capacitors. It is frequently used for chemical reactions and other applications, which require a high solvency power.


DMF was first dimtehylformamide in by the French chemist Albert Verley 8 January — 27 Novemberby distilling a mixture dimethylforamide dimethylamine hydrochloride and potassium formate.

Eastman | Dimethylformamide (DMF)

Spectral Database for Organic Compounds. The solvent properties of DMF are particularly attractive because of the high dielectric constant, the aprotic nature of the solvent, its wide liquid range and low volatility. Authorized Distributors Please select a region and country for a list of authorized distributors.

DMF is prepared by combining methyl formate and dimethylamine or by reaction of dimethylamine with carbon monoxide. DMF is also used as carrier for inks and dyes in various printing and fiber-dying applications. Chemical synthesis using supercritical fluids. As for most amidesthe spectroscopic evidence indicates partial double bond character for the C-N and C-O bonds.

The product is known as a universal solvent. If a country is not listed for a region, contact Eastman for further information. DMF is miscible with water.